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MDMA and other amphetamines
A lot of pills sold as ecstasy contain at least some of something else, so taking it during pregnancy would be a bit of a crapshoot depending on the actual contents. People who take ecstasy also often use other drugs at the same time, like alcohol, cigarettes and cocaine - all of which do have implications for the fetus.
Bottom line, if you or someone else is pregnant and already used ecstasy once, it's probably ok but you'd do better to avoid using it again before delivery. If you haven't used it during pregnancy, definitely stick with that. You pretty much have to err on the side of caution with pregnancy, because you don't know your preexisting risk of complications and no one knows definitely what substances are safe. Keep it natural.