Flumazenil molecule
Medical treatment for cocaine addiction is controversial and at present there are no federally approved medications specifically designed for cocaine dependence. However, there are some treatments available for addicts that use medications off-label. When a medication is used "off-label", a physician is prescribing it for a purpose beyond its original scope.
- Prometa®
- Developed by Hythiam, Inc., Prometa is a not a drug per se, but a treatment protocol that consists of combination drug treatment plus therapy. The drug regimen, designed to eliminate cravings, comprises flumazenil, hydroxyzine, and gabapentin. The therapy has not been widely researched but has been widely used, not only in private settings but by the criminal justice system. Prometa is controversial, detractors accusing Hythiam of funneling money to proponents.
- CPP-109 (Vigabitrin)
- Catalyst Pharmaceuticals has designated vigabitrin as CPP-109. The FDA has approved CPP-109 for clinical trials and Fast Track approval status as a treatment for cocaine and metaamphetamine addiction.
- Carbamazapine
- This anti-convulsion drug, generally given to patients with eplilepsy, has been experimented with as a potential treatment for cocaine addiction but studies have not shown it to be effective.
- Antidepressants
- Seratonin reuptake inhibitors have been theorized as a treatment for cocaine addiction but studies have not been promising.
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